تعداد نشریات | 44 |
تعداد شمارهها | 1,303 |
تعداد مقالات | 16,020 |
تعداد مشاهده مقاله | 52,489,281 |
تعداد دریافت فایل اصل مقاله | 15,216,899 |
اثر تزریق اسید آسکوربیک و مس بر غلظت فراسنجههای سرم و بروز ناهنجاریهای متابولیکی در گاوهای دوره انتقال تحت تنش گرمایی | ||
پژوهش های علوم دامی (دانش کشاورزی) | ||
دوره 34، شماره 1، خرداد 1403، صفحه 45-61 اصل مقاله (581.25 K) | ||
نوع مقاله: مقاله پژوهشی | ||
شناسه دیجیتال (DOI): 10.22034/as.2023.55421.1697 | ||
نویسندگان | ||
هوشنگ جعفری* 1؛ فرشید فتاح نیا2؛ شریف خدامرادی3؛ گلناز تأسلی4 | ||
1بخش تحقیقات علوم دامی، مرکزتحقیقات و آموزش کشاورزی و منابع طبیعی استان ایلام، سازمان تحقیقات، آموزش و ترویج کشاورزی، ایران. | ||
2هیئت علمی گروه علوم دامی دانشگاه ایلام | ||
3سازمان جهاد کشاورزی ایلام | ||
4استادیار پژوهشی بخش تحقیقات علوم دامی، مرکز تحقیقات و آموزش کشاورزی و منابع طبیعی استان چهارمحال و بختیاری. | ||
چکیده | ||
زمینه مطالعاتی: دوره انتقال پرتنشترین دوره فیزیولوژیکی برای گاوهای شیری بوده و بهدلیل تضعیف سیستم ایمنی اکثر بیماریهای متابولیکی و عفونی در این دوره اتفاق میافتد. یکی از راهکارهای بهبود عملکرد سیستم ایمنی در طی دوره انتقال استفاده از مکملهای ویتامینی و معدنی است. هدف: این آزمایش بهمنظور مطالعه تأثیر تزریق ویتامین C و مس در گاوهای دوره انتقال انجام شد. روش کار: تیمارهای آزمایشی شامل شاهد (تزریق 7 میلیلیتر سرم فیزیولوژیک 9/0 درصد)، مس (تزریق 75 میلیگرم مس به هر رأس گاو)، ویتامین C (تزریق 25 میلیگرم ویتامین C به ازای هرکیلوگرم وزن زنده)، و مس-ویتامین C ( تزریق همزمان 25 میلیگرم ویتامین C به ازای هر کیلوگرم وزن زنده و 75 میلیگرم مس به هر رأس) بودند. آزمایش در فصل تابستان بر روی 40 رأس گاو هلشتاین (20 رأس زایش دوم و 20 رأس زایش سوم و چهارم) انجام شد. تزریقها در روزهای 40 و 20 قبل از زایش مورد انتظار ، روز زایش و 20 روز پس از زایش انجام گردید. نتایج: تیمارهای آزمایشی اثری بر غلظت ویتامین C، سوپراکسید دیسموتاز، فسفر، منیزیم، گلوکز، تریگلیسرید، HDL-کلسترول، اسیدهای چرب غیراستریفیه و بتاهیدروکسی بوتیرات سرم نداشتند. تزریق همزمان ویتامین C و مس باعث افزایش غلظت مس در روزهای 10 و 20 پس از زایش و تمایل به افزایش غلظت کلسترول سرم در روز 10 و 30 پس از زایش شد. غلظت کلسیم سرم در روز زایش در گاوهای دریافت کننده همزمان ویتامین C و مس در مقایسه با سایر تیمارها تمایل به افزایش داشت. بیشترین موارد بروز جفتماندگی و ورم پستان بالینی در گاوهای گروه شاهد مشاهده شد. نتیجهگیری نهایی: بهطور کلی تزریق ویتامین C و مس به دلیل بهبود عملکرد سیستم ایمنی مانع از بروز جفتماندگی و کاهش وقوع ورم پستان در گاوهای دوره انتقال در فصل تابستان شد. | ||
کلیدواژهها | ||
تنش حرارتی؛ جفتماندگی؛ مس؛ ورم پستان؛ ویتامین C | ||
مراجع | ||
Erb C, Staudt N, Flammer J and Nau W, 2004. Ascorbic acid as a free radical scavenger in porcine and bovine aqueous humour. Ophthalmic Research 36: 38-42. Fagari- Nobijari H, Amanlou H and Dehghan Bandary M, 2013. The use of copper supplementation to improve growth performance and claw health in young holestein bulls. Journal of Agricultural Science and Technology 15: 77-86. Filappi A, Prestes D and Cecim M, 2005. Suplementação mineral para bovinos de corte sob pastejo. Revisão. Veterinária Notícias Veterinary News 11: 91–98. Gakhar G, Randhawa SS, Randhawa CS, Bansa BK and Singh RS, 2010. Effect of copper on the milk quality and prevention of mastitis in dairy cows. The Indian Journal of Animal Sciences 80: 727-728. Ganda EK, Bisinotto RS, Vasquez AK, Teixeira AGV, Machado VS, Foditsch C, Bicalho M, Lima FS, Stephens L, Gomes MS, Dias JM and Bicalho RC, 2016. Effects of injectable trace mineral supplementation in lactating dairy cows with elevated somatic cell counts. Jounal of Dairy Science 99: 1-11. Gengelbach GP, Ward JD and Spears JW, 1994. Effect of dietary copper, iron and molybdenum on growth and copper status of beef cows and calves. Journal of Animal Science 72: 2722-2727. Goetzl EJ, Wasserman SI, Gigli I and Austen KF, 1974. Enhancement of random migration and chemotactic response of human leukocytes by ascorbic acid. Journal of Clinical Investigation 53: 813-818. Goff JP, Kimura K and Horst RL, 2002. Effect of mastectomy on milk fever, energy, and vitamins A, E, and beta-carotene status at parturition. Journal of Dairy Science 85: 1427–1436. Hill GM and Shannon MC, 2019. Copper and Zinc Nutritional Issues for Agricultural Animal Production. Biological Trace Element Research 188: 148–159. Khorsandi S, Riasi A, Khorvash M, Mahyari SA, Mohammadpanah F and Ahmadi F, 2016. Lactation and reproductive performance of high producing dairy cows given sustained-release multi-trace element/vitamin ruminal bolus under heat stress condition. Livestock Science 187: 146-150. Kimura K, Goff JP, Kehrli ME and Reinhardt TA, 2002. Decreased neutrophil function as a cause of retained placenta in dairy cattle. Jounal of Dairy Science 85: 544-550. Kumar A, Singh G, Kumar BVS. and Meur SK, 2011. Modulation of antioxidant status and lipid peroxidation in erythrocyte by dietary supplementation during heat stress in buffaloes. Livestock Science 138: 299–303. Kim Y, Kim H, Bae S, Choi J, Lim SY, Lee N, Kong JM, Hwang Y, Kang JS, and Lee WJ, 2013. Vitamin C is an essential factor on the anti-viral immune responses through the production of interferon-α/β at the initial stage of influenza A virus (H3N2) infection. Immune Network 3: 70-74. Kuroyanagi M, eriko S, Mihyan K, Nobuhiko A, Yoko F and Megumi O, 2002. Efects of L-ascorbic acid on lysyl oxidase in the formation of collagen cross-links. Bioscience Biotechnology and Biochemistry 66: 2077– 2082. Lohakare JD, Ryu MH, Hahn TW, Lee JK and Chae BJ, 2005. Effects of supplemental ascorbic acid on the performance and immunity of commercial broilers. Journal of Applied Poultry Research 14: 10–19. López-Alonso M and Miranda M, 2020. Copper Supplementation, A Challenge in Cattle. Animals 10:1-21. Machado VS, Oikonomou G, Lima SF, Bicalhoa MLS, Kacar C, Foditsch C, Felippeb MJ, Gilbert RO and Bicalho RC, 2014. The effect of injectable trace minerals (selenium, copper, zinc, and manganese) on peripheral blood leukocyte activity and serum superoxide dismutase activity of lactating Holstein cows. The Veterinary Journal 200: 299–304. Macleod DD, Zhang X, Ozimeck L and Kennelly JJ, 1999. Ascorby L-2-polyphosphate as a source of ascorbic acid for dairy cattle. Milchwissenschaft 54: 123–126. McCauley LK, Koh AJ, Beecher CA, Cui Y, Rosol TJ, and Franceschi RT, 1996. PTH/PTHrP receptor is temporally regulated during osteoblast differentiation and is associated with collagen synthesis. Journal of Cellular Biochemistry 61: 638–647. Minatel L, and Carfagnini JC, 2000. Copper deficiency and immune response in ruminants.utrition Research 20: 1519-1529. Naresh R, Dwivedi SK, Swarup D and Patra RC, 2002. Evaluation of ascorbic acid treatment in clinical and subclinical mastitis of Indian dairy cows. Asian-Australasian Journal of Animal Sciences 15: 905-911. National Research Council (NRC), 2001. Nutrient Requirements of Dairy Cattle. 7th revised edition, National Academy Press, Washington, DC. National Research Council (NRC), 2021. Nutrient requirements of dairy cattle, 8th revised edition, National Academies, Washington, DC. Nockels CF and Blair R, 1996. Antioxidants improve cattle immunity following stress. Animal Feed Science and Technology 62: 59–68. Noordhuizen J and Bonnefoy JM, 2015. Heat stress in dairy cattle: Major effects and practical management measures for prevention and control. Symbiosis Journal of Veterinary Science 1: 103-109. Overton T and Yasui T, 2014. Practical applications of trace minerals for dairy cattle. Journal of Animal Science 92: 416−426. Padilla L, Matsui T, Kamiya Y, Kamiya M, Tanaka M and Yano H, 2006. Heat stress decreases plasma vitamin C concentration in lactating cows. Livestock Science 101: 300–304. Padilla l, Matsui T, Ikeda S, Kitagawa M and Yano H, 2007. The effect of vitamin C suppplementation on plasma concenteration and uriinary excretion of vitamin C in cattle. Journal of Animal Science 85: 3367-3370. Picco SJ, Abba MC, Mattioli GA, Fazzio LE, Rosa D, De Luca JC and Dulout FN, 2004. Association between copper deficiency and DNA damage in cattle. Mutagenesis, 19: 453—456. Pogge DJ and Hansen SL, 2013. Effect of varying concenteration of vitamin C on performance, blood metabolites and carcass characteristics of steers consuming a common high sulfur (0.055% S) diet. Journal of Animal Science 91: 5754-5761. Prohaska JR and Gybina AA, 2004. Intracellular copper transport in mammals. The Journal of Nutrition 134: 1003-1006. Radostits OM, Blood DC and Gay CC, 1994. Veterinary Medicine. Bailliere Tindall, London, UK. Ranjan R, Swarup D, Naresh R and Patra RC, 2005. Enhanced erythrocytic lipid peroxides and reduced plasma ascorbic acid, and alteration in blood trace elements level in dairy cows with mastitis. Veterinary Research Communications 29: 27–34. Ranjan R, Ranjan A, Dhaliwal GS and Patra RC, 2012. L-Ascorbic acid (vitamin C) supplementation to optimize health and reproduction in cattle. Veterinary Quarterly 32: 145–150. Roth JA and Kaeberle ML, 1985. In vivo effect of ascorbic acid on neutrophil function in healthy and dexamethasone treated cattle. American Journal of Veterinary Research 46: 2434–2436. Rowland JL and Niederweis M, 2013. A multicopper oxidase is required for copper resistance in Mycobacterium tuberculosis. Journal of Bacteriology 195: 3724-3733. Saenko EL, Yaropolove Al and Harris ED, 1994. The biological function expressed through Copper- binding sites and a cellular receptor. The Journal of Trace Elements in Experimental Medicine 7: 69-88. SAS, 2014. Statistical Analysis System. SAS Inc., Cary, NC. Sheetal SK, Choudhary SK and Sengupta D, 2014. Mineral deficiency predisposes occurrence of retention of placenta in crossbred. Veterinary World 7: 1140-1143. Siddique K, Bawazeer N and Joy SS, 2014. Variation in macro and trace elements in progression of type 2 diabetes. Scientific World Journal 2014: 1-9. Sordillo LM, 2016. Nutritional strategies to optimize dairy cattle immunity. Journal of Dairy Science 99: 4967–4982. Sordillo LM, 2018. Symposium review: Oxylipids and the regulation of bovine mammary inflammatory responses. Journal of Dairy Science 101: 5 629–5641. Sordillo LM and Aitken SL, 2009. Impact of oxidative stress on the health and immune function of dairy cattle. Veterinary Immunology and Immunopathology 128: 104–109. Spears JW, 1999. Reevaluation of the metabolic essentiality of the minerals-review. Asian-Australasian Journal of Animal Sciences 12: 1002-1008. Spears JW, Kegley EB, and Mullis LA, 2004. Bioavailability of copper from tribasic copper and copper sulfate in growing cattle. Animal Feed Science and Technology 116: 1-13. Spolders M, Holtershinken M, Ulrich M, Rehage J and Flachowsky G, 2010. Assessment of reference values for copper and zinc in blood serum of first and second lactating dairy cows. Veterinary Medicine International 1: 1- 8. Suttle NF, 2010. Mineral Nutrition of Livestock. (4th Ed.). CABI, Cambridge. UK. Teixeira AGV, Lima FS, Bicalho MLS, Kussler A, Lima SF, Felippe MJ and Bicalho RC, 2014. Effect of an injectable trace mineral supplement containing selenium, copper, zinc, and manganese on immunity, health, and growth of dairy calves. Jounal of Dairy Science 97: 1-11. Torre PM, Harmon RJ, Hemken RW, Clark TW, Trammell DS and Smith BA, 1996. Mild dietary copper insufficiency depresses blood neutrophil function in dairy cattle. Journal of Nutritional Immunology 4: 3–24. Tyler PJ and Cummins KA, 2003. Effect of dietary ascorbyl-2- phosphate on immune function after transport to a feeding facility. Jounal of Dairy Science 86: 622-629. Van Knegsel A, Van der Meulen J and Lammers A, 2008. Nutritional effects on development and function of the mucosal immune system with a focus on pigs and poultry. Report ASG for Product Board Animal Feed, The Netherlands pp 120. Van Soest PJ, Robertson JB and Lewis BA, 1991. Methods for dietary fiber, neutral detergent fiber, and non-starch polysaccharides in relation to animal nutrition. Jounal of Dairy Science 74: 3593-3597. Vermunt JJ and West DM, 1994. Predicting Cu status in beef cattle using serum Cu concentrations. New Zealand Veterinary Journal 42: 194–195. Wankhade PR, Manimaran1 A, Kumaresan A, Jeyakumar S, Ramesha KP, Sejian V, Rajendran D. and Varghese MR, 2017. Metabolic and immunological changes in transition dairy cows: A review. Veterinary World 10: 1367-1377. Ward JD, Spears JW and Kegley EB, 1996. Bioavailability of copper proteinate and copper carbonate relative to copper sulfate in cattle. Jounal of Dairy Science 79: 127-132. Weiss WP, 2001. Effeect of dietary vitamin C on concenteration of ascorbic acid in plasma and milk. Jounal of Dairy Science 84: 2302- 2307. Wolf G, 1993. Uptake of ascorbic acid by human neutrophils. Nutrition Reviews 51: 337-338. Yang ZB, Yang WR, Zhang SZ, Li ZY and Zhao H, 2007. Effect of copper and zinc on blood and milk parameters and performance of dairy cows. Journal of Animal and Feed Sciences 16: 571-575. Yatoo MI, Saxena A, Deepa PM, Habeab BP and Devi S, 2013. Role of trace elements in animals: a review. Veterinary World 6: 963-967. Yost GP, Arthington JD, Mc dowell LR, Martin FG, Wilkinson NS and Swensen CK, 2002. Effect of copper source and level on the rate and extent of copper repletion in Holestein Heifers. Jounal of Dairy Science 85: 3297- 3303. Zubay G, 1993. Biochemistry. (3rd Ed.). Brown Publisher, Oxford, UK. | ||
آمار تعداد مشاهده مقاله: 269 تعداد دریافت فایل اصل مقاله: 128 |