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Memarbashi, Reza, Ghasemabadi, Atena, Ebadi, Zahra. (1401). Backward bifurcation in a two strain model of heroin addiction. سامانه مدیریت نشریات علمی, 10(3), 656-673. doi: 10.22034/cmde.2021.44619.1881
Reza Memarbashi; Atena Ghasemabadi; Zahra Ebadi. "Backward bifurcation in a two strain model of heroin addiction". سامانه مدیریت نشریات علمی, 10, 3, 1401, 656-673. doi: 10.22034/cmde.2021.44619.1881
Memarbashi, Reza, Ghasemabadi, Atena, Ebadi, Zahra. (1401). 'Backward bifurcation in a two strain model of heroin addiction', سامانه مدیریت نشریات علمی, 10(3), pp. 656-673. doi: 10.22034/cmde.2021.44619.1881
Memarbashi, Reza, Ghasemabadi, Atena, Ebadi, Zahra. Backward bifurcation in a two strain model of heroin addiction. سامانه مدیریت نشریات علمی, 1401; 10(3): 656-673. doi: 10.22034/cmde.2021.44619.1881

Backward bifurcation in a two strain model of heroin addiction

Computational Methods for Differential Equations
مقاله 7، دوره 10، شماره 3، مهر 2022، صفحه 656-673    اصل مقاله (1.36 M)
نوع مقاله: Research Paper
شناسه دیجیتال (DOI): 10.22034/cmde.2021.44619.1881
نویسندگان
Reza Memarbashi* 1؛ Atena Ghasemabadi2؛ Zahra Ebadi1
1Department of Mathematics, Semnan University, P. O. Box 35195-363, Semnan, Iran.
2Esfarayen University of Technology, Esfarayen, North Khorasan, Iran.
چکیده
Among the various causes of heroin addiction, the use of prescription opioids is one of the main reasons. In this article, we introduce and analyze a two-strain epidemic model with the superinfection for modeling the effect of prescribed opioids abuse on heroin addiction. Our model contains the impact of relapse of individuals under treatment/rehabilitation to drug abuse in each strain. We extract the basic reproductive ratio, the invasion numbers and study the occurrence of backward bifurcation in strain dominance equilibria, i.e., boundary equilibria. Also, we explore both the local and global stability of DFE and boundary equilibria under suitable conditions. Furthermore, we study the existence of the coexistence equilibrium point. We prove that when R0 < 1, the coexistence equilibrium point can exist, i.e., backward bifurcation occurs in coexistence equilibria. Finally, we use numerical simulation to describe the obtained analytical results. 
کلیدواژه‌ها
Epidemic model؛ Multiple strain؛ Superinfection؛ Global stability؛ Backward bifurcation
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